PRF Microneedling
The next evolution of the Vampire Facial - combining SkinPen® microneedling with Platelet-Rich Fibrin (PRF) for deeper, longer-lasting collagen stimulation using only your own biology.
What Is PRF Microneedling?
PRF Microneedling is an advanced regenerative skin treatment that pairs FDA-cleared SkinPen® microneedling with Platelet-Rich Fibrin (PRF) - a highly concentrated form of your own blood's healing proteins. The result is a treatment that stimulates collagen and elastin production from two synergistic directions at once.
You may have heard of the Vampire Facial® - microneedling paired with PRP. PRF Microneedling works on the same principle, but PRF is a newer, more refined technology that delivers a higher concentration of growth factors and releases them gradually over 1–2 weeks rather than all at once. Sarah-Kate Rems, NP performs PRF Microneedling at her NYC practice in Manhattan, drawing on her expertise as a top regenerative aesthetics provider in New York City.
Why PRP Instead of PRF?
Slower Release. Stronger Results. PRF is processed without anticoagulants at a lower centrifuge speed, which preserves a natural fibrin matrix — essentially a biological scaffold that holds growth factors in place and releases them slowly over time. This means your skin keeps receiving collagen-stimulating signals for up to two weeks after a single session. With PRP, those signals are largely spent within a few hours. More sustained delivery = more sustained results. PRF also contains a higher concentration of platelets and growth factors than standard PRP, making it a genuinely upgraded approach.
How It Works
01
Blood Draw
A small amount of blood is drawn from your arm — the same as a routine lab draw.
02
Centrifuge
Your blood is spun in a centrifuge to isolate and concentrate the platelet-rich fibrin.
03
Numbing
Topical numbing cream is applied for approximately 15 minutes for a comfortable experience.
04
SkinPen® Microneedling
FDA-cleared SkinPen® creates precise microchannels in the skin to trigger natural collagen production.
05
PRF Application
Your PRF is applied topically and massaged into the microchannels as microneedling progresses.
06
PRF Mask
Remaining PRF is left on the skin as a mask for a few hours post-treatment to maximize absorption.
Benefits of PRF Microneedling
Slower Release. Stronger Results. PRF is processed without anticoagulants at a lower centrifuge speed, which preserves a natural fibrin matrix — essentially a biological scaffold that holds growth factors in place and releases them slowly over time. This means your skin keeps receiving collagen-stimulating signals for up to two weeks after a single session. With PRP, those signals are largely spent within a few hours. More sustained delivery = more sustained results. PRF also contains a higher concentration of platelets and growth factors than standard PRP, making it a genuinely upgraded approach.
Are You a Good Candidate for PRF Microneedling in NYC
PRF Microneedling is appropriate for most skin types and tones. It's an ideal treatment if you want to address early signs of aging, improve skin quality, or take your existing microneedling results to the next level.
PRF Microneedling NYC — Common Questions
Q: What is PRF Microneedling? PRF Microneedling combines FDA-cleared SkinPen® microneedling with Platelet-Rich Fibrin (PRF) derived from your own blood. Microneedling creates tiny channels in the skin that allow PRF's concentrated growth factors to absorb deeply, stimulating collagen and elastin for a brighter, firmer, and smoother complexion. It's an excellent natural skin rejuvenation treatment available in Manhattan, NYC.
Q: What's the difference between PRF Microneedling and the Vampire Facial (PRP)? The Vampire Facial® uses PRP (Platelet-Rich Plasma), while PRF Microneedling uses PRF (Platelet-Rich Fibrin). PRF is processed at a lower centrifuge speed without anticoagulants, creating a fibrin matrix that releases growth factors slowly over 1–2 weeks. PRP releases growth factors within a few hours. PRF also delivers a higher concentration of growth factors overall — making it the newer, more advanced version of the same concept.
Q: How many PRF Microneedling sessions do I need? Sarah-Kate recommends a series of 3 treatments spaced 4–6 weeks apart. Each session builds on the last, with collagen production continuing to improve between appointments. Many patients see noticeable results after their first or second session, with full results developing over 2–3 months.
Q: Is there downtime after PRF Microneedling in NYC? Expect redness and mild sensitivity for 24–48 hours post-treatment — similar to a mild sunburn. Most NYC patients are comfortable returning to work or social plans the following day. Avoid direct sun exposure, makeup, and active skincare (retinols, AHAs) for 24–48 hours after your appointment.
Q: Does PRF Microneedling hurt? A topical numbing cream is applied for 15 minutes before the procedure, making treatment very well-tolerated. Most patients describe the sensation as mild pressure or warmth. SkinPen® is known for its precision and comfort compared to older microneedling devices.
Q: Can I combine PRF Microneedling with other treatments? Yes. PRF Microneedling pairs well with PRF under-eye injections for a comprehensive skin rejuvenation appointment. Sarah-Kate can also discuss how PRF Microneedling fits into a broader plan alongside dermal fillers or Botox/Daxxify.
Q: Where can I get PRF Microneedling in New York City? Sarah-Kate Rems, NP offers PRF Microneedling at her NYC practice at 240 W 37th Street, Manhattan. Book here at sarahkateremsnp.com or text 646-434-8315.